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SAR405 is a first-in-class, selective, and ATP-competitive PI3K class III (PI3KC3) isoform Vps34 inhibitor (IC50=1.2 nM; Kd=1.5 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.53 mL | 112.65 mL | 225.3 mL |
| 0.5 mM | 4.51 mL | 22.53 mL | 45.06 mL |
| 1 mM | 2.25 mL | 11.27 mL | 22.53 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.51 mL |
*The above data is based on the productmolecular weight 443.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21345 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 443.85 |
| Formula | C19H21ClF3N5O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1523406-39-4 |
| Synonyms | SAR 405, SAR-405 |
| SMILES | O=C1N(C2=NC(N3[[email protected]](C)COCC3)=C1)CC[[email protected]@H](C(F)(F)F)N2CC4=CC(Cl)=CN=C4 |
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