Catalog No.: A20836

TRPC6 inhibitor


SAR7334 Chemical Structure

CAS NO. 1333210-07-3

SAR7334 is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM.

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Biological Activity

SAR7334 is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM.
In vitro DMSO 67 mg/mL (182.12 mM)
Water Insoluble
Ethanol 67 mg/mL (182.12 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.18 mL 135.92 mL 271.84 mL
0.5 mM 5.44 mL 27.18 mL 54.37 mL
1 mM 2.72 mL 13.59 mL 27.18 mL
5 mM 0.54 mL 2.72 mL 5.44 mL

*The above data is based on the productmolecular weight 367.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20836
Actions Inhibitor
CAS No. 1333210-07-3
Formula C21H22ClN3O
M. Wt 367.87
Purity >98%
Synonyms SAR 7334, SAR-7334
SMILES N[[email protected]@H](C1)CCCN1[[email protected]@H]2CC3=CC=CC=C3[[email protected]]2OC4=C(Cl)C=C(C#N)C=C4

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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