Saroglitazar magnesium is a selective agonist of peroxisome proliferator-activated receptors PPARα and PPARγ, exhibiting high potency with EC50 values of 0.65 pM and 3 nM, respectively, in HepG2 cells. This compound plays a crucial role in lipid metabolism and glucose homeostasis, making it a valuable tool for research in metabolic disorders such as dyslipidemia and type 2 diabetes. Its dual activity on PPARα and PPARγ positions it as a significant candidate for exploring therapeutic strategies in metabolic disease models.
Saroglitazar magnesium is a selective agonist of peroxisome proliferator-activated receptors PPARα and PPARγ, exhibiting high potency with EC50 values of 0.65 pM and 3 nM, respectively, in HepG2 cells. This compound plays a crucial role in lipid metabolism and glucose homeostasis, making it a valuable tool for research in metabolic disorders such as dyslipidemia and type 2 diabetes. Its dual activity on PPARα and PPARγ positions it as a significant candidate for exploring therapeutic strategies in metabolic disease models.
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