Sarpogrelate-d3 hydrochloride

Catalog No.: A29712
Stable Isotope
Sarpogrelate-d3 hydrochloride is a deuterium-labeled form of Sarpogrelate hydrochloride, serving as a selective antagonist for the 5-HT2 receptor family. With pKis of 8.52, 6.57, and 7.43 for the 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively, it demonstrates notable selectivity over 5-HT1, 5-HT3, 5-HT4, and various adrenergic and histamine receptors. This reagent is valuable for studying vascular diseases related to thrombosis, enabling researchers to investigate the pharmacodynamics and metabolism of Sarpogrelate in biological systems.
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Adooq Products cited in reputable paper
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionSarpogrelate-d3 hydrochloride is a deuterium-labeled form of Sarpogrelate hydrochloride, serving as a selective antagonist for the 5-HT2 receptor family. With pKis of 8.52, 6.57, and 7.43 for the 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively, it demonstrates notable selectivity over 5-HT1, 5-HT3, 5-HT4, and various adrenergic and histamine receptors. This reagent is valuable for studying vascular diseases related to thrombosis, enabling researchers to investigate the pharmacodynamics and metabolism of Sarpogrelate in biological systems.
Product Information
Catalog NumA29712
FormulaC24H29D3ClNO6
Molecular Weight468.99
CAS Number2934185-00-7
SMILESCN(CC(COC1=CC=CC=C1CCC2=CC(OC([2H])([2H])[2H])=CC=C2)OC(CCC(O)=O)=O)C.Cl
SynonymsMCI-9042-d3
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