SARS-CoV-2-IN-51

Catalog No.: A53468
SARS-CoV-2 Inhibitor
SARS-CoV-2-IN-51 is an effective inhibitor targeting the fusion mechanism of the SARS-CoV-2 virus, particularly against the Omicron variant. This compound exhibits potent antiviral activity, inhibiting viral entry with EC50 values ranging from 0.82 to 5.45 μM. By directly interacting with the spike protein in its prefusion conformation, SARS-CoV-2-IN-51 serves as a valuable tool for research applications focused on COVID-19 therapeutic development and understanding viral entry mechanisms.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSARS-CoV-2-IN-51 is an effective inhibitor targeting the fusion mechanism of the SARS-CoV-2 virus, particularly against the Omicron variant. This compound exhibits potent antiviral activity, inhibiting viral entry with EC50 values ranging from 0.82 to 5.45 μM. By directly interacting with the spike protein in its prefusion conformation, SARS-CoV-2-IN-51 serves as a valuable tool for research applications focused on COVID-19 therapeutic development and understanding viral entry mechanisms.
Product Information
Catalog NumA53468
FormulaC58H85NO15
Molecular Weight1036.29
CAS Number3049478-88-5
SMILESO=C([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)([C@H](CC5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O[C@H]7[C@@H]([C@@H]([C@H]([C@@H](O7)C)O)O)O)O)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)C)([H])CC4)C)([H])CC3)C)C)NC9=CC%10=C(C=CC=C%10)C=C9
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