SB-209247 is a selective leukotriene B4 (LTB4) receptor antagonist, exhibiting high affinity with a Ki of 0.78 nM. This compound effectively inhibits LTB4-induced calcium mobilization, with an IC50 of 6.6 nM, displaying significant anti-inflammatory properties. SB-209247 is valuable for research applications focusing on inflammatory diseases and the modulation of leukotriene signaling pathways.
SB-209247 is a selective leukotriene B4 (LTB4) receptor antagonist, exhibiting high affinity with a Ki of 0.78 nM. This compound effectively inhibits LTB4-induced calcium mobilization, with an IC50 of 6.6 nM, displaying significant anti-inflammatory properties. SB-209247 is valuable for research applications focusing on inflammatory diseases and the modulation of leukotriene signaling pathways.
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