SB 216763

Catalog No.: A10825
GSK-3 inhibitor
SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3α with an IC50 value of 34 nM (similar potency for GSK3β).
Grouped product items
Size Price Stock Qty
2mg
$25.00
In stock
5mg
$35.00
In stock
10mg
$55.00
In stock
25mg
$125.00
In stock
50mg
$195.00
In stock
100mg
$335.00
In stock
500mg
$840.00
In stock
10mM * 1mL in DMSO
$40.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Biological Activity
Discription SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3α with an IC50 value of 34 nM (similar potency for GSK3β).
Targets
Target Value
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A10825
Formula C19H12Cl2N2O2
Molecular Weight 371.2
CAS Number 280744-09-4
SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl
Synonyms SB-216763, SB216763
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 21 mg/mL (56.56 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.94 mL 134.7 mL 269.4 mL
0.5 mM 5.39 mL 26.94 mL 53.88 mL
1 mM 2.69 mL 13.47 mL 26.94 mL
5 mM 0.54 mL 2.69 mL 5.39 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy SB 216763 | SB 216763 Supplier | purchase SB 216763 | SB 216763 cost | SB 216763 manufacturer | order SB 216763 | SB 216763 distributor | buy 280744-09-4 | 280744-09-4 Supplier | purchase 280744-09-4 | 280744-09-4 cost | 280744-09-4 manufacturer | order 280744-09-4 | 280744-09-4 distributor