Biological Activity
SB-242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases such as autoimmune or inflammatory diseases.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.46 mL | 142.3 mL | 284.61 mL |
0.5 mM | 5.69 mL | 28.46 mL | 56.92 mL |
1 mM | 2.85 mL | 14.23 mL | 28.46 mL |
5 mM | 0.57 mL | 2.85 mL | 5.69 mL |
*The above data is based on the productmolecular weight 351.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13678 |
---|---|
Actions | Inhibitor |
CAS No. | 193746-75-7 |
Formula | C18H17N5O3 |
M. Wt | 351.36 |
Solubility | DMSO |
Purity | >98% |
Synonyms | SB 242235, SB242235 |
SMILES | COC1=NC=CC(=N1)C2=C(N=CN2C3CCNCC3)C4=CC=C(C=C4)F |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Pamapimod (R-1503)
Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor.
SB 203580
SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.
SD-06
SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibi…
Asiatic acid
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. Asiatic acid…
Talmapimod (SCIO-469)
Talmapimod (SCIO-469) is a selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro).
DBM 1285 dihydrochloride
DBM 1285 dihydrochloride is a p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF-α production in macrophages and in viv…
AMG 548
AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blo…
VX-745
VX-745 is a small-molecule inhibitor of MAPK that is reported to be active against several isotypes of p38 MAPK, including p38α, p38βand p…
Keywords:buy SB-242235 | SB-242235 Supplier | purchase | cost | manufacturer | order | distributor | buy 193746-75-7| 193746-75-7 Supplier | purchase 193746-75-7 | 193746-75-7 cost | 193746-75-7 manufacturer | order 193746-75-7 | 193746-75-7 distributor