SB-505124

Catalog No.: A11157
ALK5 inhibitor
SB-505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5), ALK4 and ALK7 (IC50 values are 47 and 129 nM for ALK5 and ALK4 respectively).
Grouped product items
Product Name Price Stock Qty
SB-505124 5mg
Special Price $48.00 Regular Price $60.00
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SB-505124 25mg
Special Price $176.00 Regular Price $220.00
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SB-505124 50mg
Special Price $320.00 Regular Price $400.00
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SB-505124 100mg
Special Price $576.00 Regular Price $720.00
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SB-505124 10mM * 1mL in DMSO
Special Price $79.20 Regular Price $99.00
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Biological Activity
Discription SB-505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5), ALK4 and ALK7 (IC50 values are 47 and 129 nM for ALK5 and ALK4 respectively).
Targets
Target Value
Product Information
Catalog Num A11157
Formula C20H21N3O2
Molecular Weight 335.4
CAS Number 694433-59-5
SMILES CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4
Synonyms SB505124
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 65 mg/mL (193.8 mM)
Water Insoluble
Ethanol 65 mg/mL (193.8 mM)
In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 7.1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.82 mL 149.08 mL 298.15 mL
0.5 mM 5.96 mL 29.82 mL 59.63 mL
1 mM 2.98 mL 14.91 mL 29.82 mL
5 mM 0.6 mL 2.98 mL 5.96 mL
Useful Calculator

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