SB-705498

Catalog No.: A11143

TRPV1 antagonist

SB-705498

SB-705498 Chemical Structure

CAS NO. 501951-42-4

SB-705498 is a potent, selective and orally bioavailable TRPV1 antagonist.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$150.00
50 mg
$650.00
100 mg
$1,050.00
10mM * 1mL in DMSO
$85.00
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Biological Activity

SB-705498 is a potent, selective and orally bioavailable TRPV1 antagonist.
Targets
hTRPV1 hTRPV1
7.6(pKi)7.1(pIC50)
In vitro DMSO 86 mg/mL (200.35 mM)
Water <1 mg/mL (<1 mM)
Ethanol 20 mg/mL (46.59 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.36 mL 116.82 mL 233.64 mL
0.5 mM 4.67 mL 23.36 mL 46.73 mL
1 mM 2.34 mL 11.68 mL 23.36 mL
5 mM 0.47 mL 2.34 mL 4.67 mL

*The above data is based on the productmolecular weight 428.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11143
Actions Antagonist
M. Wt 428.0
Formula C17H16BrF3N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 501951-42-4
Synonyms SB705498
SMILES C1CN(C[[email protected]@H]1NC(=O)NC2=CC=CC=C2Br)C3=NC=C(C=C3)C(F)(F)F

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