SB756050

Catalog No.: A12759

TGR5 agonist

SB756050

SB756050 Chemical Structure

CAS NO. 447410-57-3

SB756050 is a selective TGR5 agonist currently in phase 1clinical trials for the treatment of type 2 diabetes.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $108.00

Special Price $86.40

5 mg

Regular Price: $324.00

Special Price $259.20

10 mg

Regular Price: $552.00

Special Price $441.60

50 mg

Regular Price: $1,656.00

Special Price $1,324.80

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Biological Activity

SB756050 is a selective TGR5 agonist currently in phase 1clinical trials for the treatment of type 2 diabetes.
In vitro DMSO 91 mg/mL (181.78 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.98 mL 99.88 mL 199.76 mL
0.5 mM 4 mL 19.98 mL 39.95 mL
1 mM 2 mL 9.99 mL 19.98 mL
5 mM 0.4 mL 2 mL 4 mL

*The above data is based on the productmolecular weight 500.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12759
Actions Agonist
CAS No. 447410-57-3
Formula C21H28N2O8S2
M. Wt 500.59
Solubility DMSO
Purity >98%
Synonyms SB-756050; SB 756050
SMILES O=S(N1CCN(S(=O)(C2=CC=C(OC)C(OC)=C2)=O)CCC1)(C3=CC=C(OC)C(OC)=C3)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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