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SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.
Targets
| Akt | ||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.41 mL | 137.07 mL | 274.14 mL |
| 0.5 mM | 5.48 mL | 27.41 mL | 54.83 mL |
| 1 mM | 2.74 mL | 13.71 mL | 27.41 mL |
| 5 mM | 0.55 mL | 2.74 mL | 5.48 mL |
*The above data is based on the productmolecular weight 364.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A15541 |
|---|---|
| Actions | Activator |
| M. Wt | 364.78 |
| Formula | C17H17ClN2O5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 305834-79-1 |
| Synonyms | SC 79, SC-79 |
| SMILES | ClC1=CC=C(OC(N)=C(C(OCC)=O)C2C(C#N)C(OCC)=O)C2=C1 |
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