SC79

Catalog No.: A15541

Akt phosphorylation activator

SC79

SC79 Chemical Structure

CAS NO. 305834-79-1

SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $85.00

Special Price $68.00

25 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $245.00

Special Price $196.00

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Biological Activity

SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.
Targets
Akt
In vitro (25°C) DMSO 61 mg/mL (167.22 mM)
Water Insoluble
Ethanol Warmed: 61 mg/mL (167.22 mM)
In vivo 2% DMSO+corn oil 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.41 mL 137.07 mL 274.14 mL
0.5 mM 5.48 mL 27.41 mL 54.83 mL
1 mM 2.74 mL 13.71 mL 27.41 mL
5 mM 0.55 mL 2.74 mL 5.48 mL

*The above data is based on the productmolecular weight 364.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15541
Actions Activator
CAS No. 305834-79-1
Formula C17H17ClN2O5
M. Wt 364.78
Purity >98%
Synonyms SC 79, SC-79
SMILES ClC1=CC=C(OC(N)=C(C(OCC)=O)C2C(C#N)C(OCC)=O)C2=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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