SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.
SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.
Targets
Target
Value
Product Information
Catalog Num
A15541
Formula
C17H17ClN2O5
Molecular Weight
364.78
CAS Number
305834-79-1
SMILES
ClC1=CC=C(OC(N)=C(C(OCC)=O)C2C(C#N)C(OCC)=O)C2=C1
Synonyms
SC 79, SC-79
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
61 mg/mL (167.22 mM)
Water
Insoluble
Ethanol
Warmed: 61 mg/mL (167.22 mM)
In vivo
2% DMSO+corn oil
4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: