SC79

Catalog No.: A15541
Akt phosphorylation activator
SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.
Grouped product items
Product Name Price Stock Qty
SC79 10mg
$85.00
In stock
SC79 25mg
$160.00
In stock
SC79 50mg
$245.00
In stock
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Biological Activity
Discription SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.
Targets
Target Value
Product Information
Catalog Num A15541
Formula C17H17ClN2O5
Molecular Weight 364.78
CAS Number 305834-79-1
SMILES ClC1=CC=C(OC(N)=C(C(OCC)=O)C2C(C#N)C(OCC)=O)C2=C1
Synonyms SC 79, SC-79
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 61 mg/mL (167.22 mM)
Water Insoluble
Ethanol Warmed: 61 mg/mL (167.22 mM)
In vivo 2% DMSO+corn oil 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.41 mL 137.07 mL 274.14 mL
0.5 mM 5.48 mL 27.41 mL 54.83 mL
1 mM 2.74 mL 13.71 mL 27.41 mL
5 mM 0.55 mL 2.74 mL 5.48 mL
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