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Biological Activity
SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.
Targets
| Akt | ||||
| In vitro (25°C) | DMSO | 61 mg/mL (167.22 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 61 mg/mL (167.22 mM) | ||
| In vivo | 2% DMSO+corn oil | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.41 mL | 137.07 mL | 274.14 mL |
| 0.5 mM | 5.48 mL | 27.41 mL | 54.83 mL |
| 1 mM | 2.74 mL | 13.71 mL | 27.41 mL |
| 5 mM | 0.55 mL | 2.74 mL | 5.48 mL |
*The above data is based on the productmolecular weight 364.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15541 |
|---|---|
| Actions | Activator |
| CAS No. | 305834-79-1 |
| Formula | C17H17ClN2O5 |
| M. Wt | 364.78 |
| Purity | >98% |
| Synonyms | SC 79, SC-79 |
| SMILES | ClC1=CC=C(OC(N)=C(C(OCC)=O)C2C(C#N)C(OCC)=O)C2=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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