SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding, with an IC50 value of 20 nM in rabbit microsomal membranes. Antisecretory and cytoprotective activities.
SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding, with an IC50 value of 20 nM in rabbit microsomal membranes. Antisecretory and cytoprotective activities.
Product Information
Catalog Num
A19424
Formula
C17H15N3O
Molecular Weight
277.32
CAS Number
76081-98-6
SMILES
N#CCC1=C(C)N=C2C(OCC3=CC=CC=C3)=CC=CN21
Synonyms
SCH 28080; SCH-28080
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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