Sch412348 is a highly potent competitive antagonist of the human adenosine A2A receptor, exhibiting a Ki value of 0.6 nM and demonstrating over 1000-fold selectivity against other adenosine receptor subtypes. This selectivity makes Sch412348 a valuable tool for studying adenosine signaling pathways. It is particularly relevant in research focusing on neurological disorders, cardiovascular conditions, and cancer, where modulation of adenosine receptors may provide therapeutic insights.
Sch412348 is a highly potent competitive antagonist of the human adenosine A2A receptor, exhibiting a Ki value of 0.6 nM and demonstrating over 1000-fold selectivity against other adenosine receptor subtypes. This selectivity makes Sch412348 a valuable tool for studying adenosine signaling pathways. It is particularly relevant in research focusing on neurological disorders, cardiovascular conditions, and cancer, where modulation of adenosine receptors may provide therapeutic insights.
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