SD-208

Catalog No.: A14066

TGF-βR Inhibitor

SD-208

SD-208 Chemical Structure

CAS NO. 627536-09-8

SD-208 is a potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50= 49 nM); displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively.

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$260.00
50 mg
$450.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SD-208 is a potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50= 49 nM); displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively.
Targets
TGF-βRI (ALK5)
48 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.35 mL 141.74 mL 283.49 mL
0.5 mM 5.67 mL 28.35 mL 56.7 mL
1 mM 2.83 mL 14.17 mL 28.35 mL
5 mM 0.57 mL 2.83 mL 5.67 mL

*The above data is based on the productmolecular weight 352.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14066
Actions Inhibitor
M. Wt 352.75
Formula C17H10ClFN6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 627536-09-8
Synonyms SD 208, SD208
SMILES C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy SD-208 | SD-208 Supplier | purchase SD-208 | SD-208 cost | SD-208 manufacturer | order SD-208 | SD-208 distributor | buy 627536-09-8| 627536-09-8 Supplier | purchase 627536-09-8 | 627536-09-8 cost | 627536-09-8 manufacturer | order 627536-09-8 | 627536-09-8 distributor
Rewards