SD-208
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | SD-208 is a potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50= 49 nM); displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively. | ||
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Catalog Num | A14066 |
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Formula | C17H10ClFN6 |
Molecular Weight | 352.75 |
CAS Number | 627536-09-8 |
SMILES | C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F |
Synonyms | SD 208, SD208 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 8 mg/mL (22.68 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 1% methylcellulose | 7 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 28.35 mL | 141.74 mL | 283.49 mL |
0.5 mM | 5.67 mL | 28.35 mL | 56.7 mL |
1 mM | 2.83 mL | 14.17 mL | 28.35 mL |
5 mM | 0.57 mL | 2.83 mL | 5.67 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2