SEL120-34A

Catalog No.: A17086

CDK8 inhibitor

SEL120-34A

SEL120-34A Chemical Structure

CAS NO. 1609522-33-9

SEL120-34A is a potent and selective CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains.

Availability: In stock

Package Price Qty
1 mg
$100.00
5 mg
$300.00
10 mg
$450.00
50 mg
$1,400.00
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Biological Activity

SEL120-34A is a potent and selective CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains.
In vitro DMSO 9 mg/mL (19.97 mM)
Water 77 mg/mL (170.88 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.15 mL 120.73 mL 241.46 mL
0.5 mM 4.83 mL 24.15 mL 48.29 mL
1 mM 2.41 mL 12.07 mL 24.15 mL
5 mM 0.48 mL 2.41 mL 4.83 mL

*The above data is based on the productmolecular weight 414.145. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17086
Actions Inhibitor
CAS No. 1609522-33-9
Formula C15H18Br2N4
M. Wt 414.145
Purity >98%
Synonyms SEL 120-34A, SEL-120-34A, SEL12034A, SEL 12034A, SEL-12034A
SMILES CC1=C2C3=C(C(Br)=C1Br)CCCN3C(N4CCNCC4)=N2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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