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SEL120-34A HCl

Catalog No.: A21485

CDK8 inhibitor

SEL120-34A HCl

SEL120-34A HCl Chemical Structure

CAS NO. 1609452-30-3

SEL120-34A HCl is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.

Availability: In stock

Package Price Qty
5 mg
$144.00
10 mg
$248.00
50 mg
$736.00
100 mg
$1,472.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SEL120-34A HCl is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.19 mL 110.96 mL 221.93 mL
0.5 mM 4.44 mL 22.19 mL 44.39 mL
1 mM 2.22 mL 11.1 mL 22.19 mL
5 mM 0.44 mL 2.22 mL 4.44 mL

*The above data is based on the productmolecular weight 450.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21485
Actions Inhibitor
CAS No. 1609452-30-3
Formula C15H18Br2N4.HCl
M. Wt 450.6
Purity >98%
SMILES CC1=C2C3=C(CCCN3C(=N2)N4CCNCC4)C(=C1Br)Br.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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