Biological Activity
SEL120-34A HCl is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.
Catalog Num | A21485 |
---|---|
Actions | Inhibitor |
Formula | C15H18Br2N4.xHCl |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1609452-30-3 |
SMILES | CC1=C(Br)C(Br)=C2C3=C1N=C(N4CCNCC4)N3CCC2.[x HCl] |
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