SEL120-34A HCl

Catalog No.: A21485

CDK8 inhibitor

SEL120-34A HCl

SEL120-34A HCl Chemical Structure

CAS NO. 1609452-30-3

SEL120-34A HCl is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.

Availability: In stock

Package Price Qty
5 mg
$144.00
10 mg
$248.00
50 mg
$736.00
100 mg
$1,472.00
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Biological Activity

SEL120-34A HCl is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity.
Catalog Num A21485
Actions Inhibitor
CAS No. 1609452-30-3
Formula C15H18Br2N4.xHCl
Solubility DMSO
Purity >98%
SMILES CC1=C(Br)C(Br)=C2C3=C1N=C(N4CCNCC4)N3CCC2.[x HCl]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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