SirReal2

Catalog No.: A15902

Selective SIRT2 inhibitor

SirReal2

SirReal2 Chemical Structure

CAS NO. 709002-46-0

SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.

Availability: In stock

Package Price Qty
5 mg
$75.00
10 mg
$140.00
25 mg
$279.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Yang Li, .et al. SIRT2 Promotes the Migration and Invasion of Gastric Cancer through RAS/ERK/JNK/MMP-9 Pathway by Increasing PEPCK1-Related Metabolism, Neoplasia, 2018, Jul; 20(7): 745-756 PMID: 29925042

Biological Activity

SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.
Targets
SIRT2
140 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.78 mL 118.89 mL 237.78 mL
0.5 mM 4.76 mL 23.78 mL 47.56 mL
1 mM 2.38 mL 11.89 mL 23.78 mL
5 mM 0.48 mL 2.38 mL 4.76 mL

*The above data is based on the productmolecular weight 420.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15902
Actions Inhibitor
M. Wt 420.55
Formula C22H20N4OS2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 709002-46-0
SMILES CC1=NC(SCC(NC2=NC=C(CC3=C(C=CC=C4)C4=CC=C3)S2)=O)=NC(C)=C1

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