SIRT2-IN-11

Name: SIRT2-IN-11
Brand: Adooq Bioscience
SKU: A56979
Rating: 5 (288 reviews)

Catalog No.: A56979

SIRT2 Inhibitor

SIRT2-IN-11 is a selective inhibitor of the SIRT2 enzyme, exhibiting an IC50 value of 18.5 μM. This compound induces apoptosis in a p53-dependent manner, leading to the upregulation of CDKN1A, PUMA, and NOXA, along with increased p53 acetylation. SIRT2-IN-11 is a valuable tool for investigating p53-related cancer mechanisms and therapeutic strategies.

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SIRT2-IN-11 1005095-06-6 SIRT2 Inhibitor

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Grouped product items
Size	Price	Stock
1mg	$30.00	In stock
5mg	$70.00	In stock
10mg	$115.00	In stock
25mg	$235.00	In stock
50mg	$350.00	In stock
100mg	$510.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	SIRT2-IN-11 is a selective inhibitor of the SIRT2 enzyme, exhibiting an IC50 value of 18.5 μM. This compound induces apoptosis in a p53-dependent manner, leading to the upregulation of CDKN1A, PUMA, and NOXA, along with increased p53 acetylation. SIRT2-IN-11 is a valuable tool for investigating p53-related cancer mechanisms and therapeutic strategies.

Product Information

Catalog Num	A56979
Formula	C21H22N2O
Molecular Weight	318.41
CAS Number	1005095-06-6
SMILES	O=C(C1=CC=C2NC(C3C(C4CCC3C4)C2=C1)C5=CC=CC=C5)N

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