Total item
Cart Subtotal
$0.00 Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
- Hae Jin Kim, .et al. Potentiation of endothelium-dependent vasorelaxation of mesenteric arteries from spontaneously hypertensive rats by gemigliptin, a dipeptidyl peptidase-4 inhibitor class of anti-diabetic drug, Korean J Physiol Pharmacol, 2018, Nov; 22(6): 713-719 PMID: 30402032
- Chintan N. Koyani, .et al. Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes, Front Physiol, 2018, 9: 1622 PMID: 30487758
Biological Activity
Sitagliptin is an oral antihyperglycemic (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class.
| In vitro | DMSO | 79 mg/mL (193.95 mM) | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.55 mL | 122.76 mL | 245.51 mL |
| 0.5 mM | 4.91 mL | 24.55 mL | 49.1 mL |
| 1 mM | 2.46 mL | 12.28 mL | 24.55 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.91 mL |
*The above data is based on the productmolecular weight 407.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14377 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 486460-32-6 |
| Formula | C16H15F6N5O |
| M. Wt | 407.31 |
| Purity | >98% |
| Synonyms | MK-0431, MK 0431, MK0431 |
| SMILES | C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Sitagliptin | Sitagliptin Supplier | purchase | cost | manufacturer | order | distributor | buy 486460-32-6| 486460-32-6 Supplier | purchase 486460-32-6 | 486460-32-6 cost | 486460-32-6 manufacturer | order 486460-32-6 | 486460-32-6 distributor
Adooq Quality Guarantee
We promise all products perform as described.