Sitagliptin
Sitagliptin is an oral antihyperglycemic (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class.
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Adooq Products cited in reputable paper
Adooq's Sitagliptin has been cited by 2 publications
- Hae Jin Kim, .et al. , Korean J Physiol Pharmacol, 2018, Nov; 22(6): 713-719 PMID: 30402032
- Chintan N. Koyani, .et al. , Front Physiol, 2018, 9: 1622 PMID: 30487758
Biological Activity
| Description | Sitagliptin is an oral antihyperglycemic (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
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Product Information
| Catalog Num | A14377 |
|---|---|
| Formula | C16H15F6N5O |
| Molecular Weight | 407.31 |
| CAS Number | 486460-32-6 |
| SMILES | C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N |
| Synonyms | MK-0431, MK 0431, MK0431 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 79 mg/mL (193.95 mM) | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.55 mL | 122.76 mL | 245.51 mL |
| 0.5 mM | 4.91 mL | 24.55 mL | 49.1 mL |
| 1 mM | 2.46 mL | 12.28 mL | 24.55 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.91 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
