SKA-111 is a selective activator of the potassium channel KCa 3.1, promoting membrane hyperpolarization in porcine endothelial cells. This compound enhances Bradykinin induced coronary dilations in isolated rat heart models. SKA-111 is valuable for cardiovascular disease research, particularly in studies exploring potassium channel modulation and endothelial function.
SKA-111 is a selective activator of the potassium channel KCa 3.1, promoting membrane hyperpolarization in porcine endothelial cells. This compound enhances Bradykinin induced coronary dilations in isolated rat heart models. SKA-111 is valuable for cardiovascular disease research, particularly in studies exploring potassium channel modulation and endothelial function.
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