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SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.63 mL | 168.15 mL | 336.3 mL |
| 0.5 mM | 6.73 mL | 33.63 mL | 67.26 mL |
| 1 mM | 3.36 mL | 16.82 mL | 33.63 mL |
| 5 mM | 0.67 mL | 3.36 mL | 6.73 mL |
*The above data is based on the productmolecular weight 297.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21893 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 297.35 |
| Formula | C16H12FN3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 72873-74-6 |
| Synonyms | SKF86002, SKF 86002 |
| SMILES | FC1=CC=C(C2=C(C3=CC=NC=C3)N4C(SCC4)=N2)C=C1 |
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