SKF-86002

Catalog No.: A21893

p38 MAP kinase inhibitor

SKF-86002

SKF-86002 Chemical Structure

CAS NO. 72873-74-6

SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM).

Availability: In stock

Package Price Qty
5 mg
$135.00
10 mg
$233.00
50 mg
$690.00
100 mg
$1,380.00
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Biological Activity

SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.63 mL 168.15 mL 336.3 mL
0.5 mM 6.73 mL 33.63 mL 67.26 mL
1 mM 3.36 mL 16.82 mL 33.63 mL
5 mM 0.67 mL 3.36 mL 6.73 mL

*The above data is based on the productmolecular weight 297.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21893
Actions Inhibitor
M. Wt 297.35
Formula C16H12FN3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 72873-74-6
Synonyms SKF86002, SKF 86002
SMILES FC1=CC=C(C2=C(C3=CC=NC=C3)N4C(SCC4)=N2)C=C1

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