SMER-3

Catalog No.: A13253

Ubiquitin E3 Ligase Inhibitor

SMER-3 Chemical Structure

CAS NO. 67200-34-4

SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation.

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$240.00
50 mg
$450.00
100 mg
$850.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 44.61 mL 223.04 mL 446.07 mL
0.5 mM 8.92 mL 44.61 mL 89.21 mL
1 mM 4.46 mL 22.3 mL 44.61 mL
5 mM 0.89 mL 4.46 mL 8.92 mL

*The above data is based on the productmolecular weight 224.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13253
Actions Inhibitor
M. Wt 224.18
Formula C11H4N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 67200-34-4
Synonyms SMER 3, SMER3
SMILES C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O

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