SMER-3

Catalog No.: A13253

Ubiquitin E3 Ligase Inhibitor

SMER-3

SMER-3 Chemical Structure

CAS NO. 67200-34-4

SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation.

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$240.00
50 mg
$450.00
100 mg
$850.00
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Biological Activity

SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 44.61 mL 223.04 mL 446.07 mL
0.5 mM 8.92 mL 44.61 mL 89.21 mL
1 mM 4.46 mL 22.3 mL 44.61 mL
5 mM 0.89 mL 4.46 mL 8.92 mL

*The above data is based on the productmolecular weight 224.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13253
Actions Inhibitor
CAS No. 67200-34-4
Formula C11H4N4O2
M. Wt 224.18
Purity >98%
Synonyms SMER 3, SMER3
SMILES C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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