SP Inhibitor 1 is a selective inhibitor of the SARS-CoV-2 spike protein, exhibiting an IC50 of 3.26 μM, while demonstrating minimal inhibition of Mpro and PLpro above 25 μM. This compound effectively inhibits SARS-CoV-2 replication in vitro at non-toxic concentrations ranging from 0.325 to 5.98 μM. SP Inhibitor 1 possesses significant cellular antiviral activity, making it a valuable tool for research applications focused on understanding and combating SARS-CoV-2.
SP Inhibitor 1 is a selective inhibitor of the SARS-CoV-2 spike protein, exhibiting an IC50 of 3.26 μM, while demonstrating minimal inhibition of Mpro and PLpro above 25 μM. This compound effectively inhibits SARS-CoV-2 replication in vitro at non-toxic concentrations ranging from 0.325 to 5.98 μM. SP Inhibitor 1 possesses significant cellular antiviral activity, making it a valuable tool for research applications focused on understanding and combating SARS-CoV-2.
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