SP27

Name: SP27
Brand: Adooq Bioscience
SKU: A56892
Rating: 5 (288 reviews)

Catalog No.: A56892

PROTAC PLK4 Degrader

SP27 is a PROTAC that selectively degrades Polo-like kinase 4 (PLK4), exhibiting a DC50 of 19.5 nM. This compound is valuable for investigating the role of PLK4 in cellular processes and is particularly relevant in breast cancer research, enabling studies on potential therapeutic applications and mechanisms of action related to oncogenesis.

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Grouped product items
Size	Price	Stock
5mg	$680.00	In stock
10mg	$1,185.00	In stock
25mg	$2,485.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Biological Activity

Description	SP27 is a PROTAC that selectively degrades Polo-like kinase 4 (PLK4), exhibiting a DC50 of 19.5 nM. This compound is valuable for investigating the role of PLK4 in cellular processes and is particularly relevant in breast cancer research, enabling studies on potential therapeutic applications and mechanisms of action related to oncogenesis.

Product Information

Catalog Num	A56892
Formula	C40H40F2N12O5
Molecular Weight	806.82
CAS Number	3034805-75-6
SMILES	FC1=CC=C(C(F)=C1)CNC2=NC3=C(C=NN3C4CCN(CC4)C(C5CCN(CC5)C6=CC7=C(C=C6)C(N(C7=O)C8C(NC(CC8)=O)=O)=O)=O)C(NC9=NNC(C)=C9)=N2

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