Catalog No.: A10860

JNK inhibitor


SP600125 Chemical Structure

CAS NO. 129-56-6

SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $40.00

Special Price $32.00

25 mg

Regular Price: $50.00

Special Price $40.00

50 mg

Regular Price: $65.00

Special Price $52.00

200 mg

Regular Price: $130.00

Special Price $104.00

10mM * 1mL in DMSO
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.


SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3.
Target Value
JNK1IC50: 40nM
JNK2IC50: 40nM
AuroraAIC50: 60nM
TrkAIC50: 70nM
JNK3IC50: 90nM
FLT3IC50: 90nM
MKK4IC50: 0.4μM
MKK6IC50: 1.0μM
PKBIC50: 1.0μM
MKK3IC50: 1.5μM
PKCαIC50: 1.5μM
p56LCKIC50: 4.3μM
MKK7IC50: 5.1μM
MEKK1IC50: >10μM
ERK2IC50: >10μM
p38βIC50: >10μM
PKAIC50: >10μM
PKCIC50: >10μM
PKCθIC50: >10μM
Chk1IC50: >10μM
EGFIC50: >10μM
IKK1IC50: >10μM
IKK2IC50: >10μM
In vitro (25°C) DMSO 44 mg/mL (199.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 45.41 mL 227.07 mL 454.13 mL
0.5 mM 9.08 mL 45.41 mL 90.83 mL
1 mM 4.54 mL 22.71 mL 45.41 mL
5 mM 0.91 mL 4.54 mL 9.08 mL

*The above data is based on the productmolecular weight 220.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10860
Actions Inhibitor
M. Wt 220.2
Formula C14H8N2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 129-56-6
Synonyms N/A

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy SP600125 | SP600125 Supplier | purchase SP600125 | SP600125 cost | SP600125 manufacturer | order SP600125 | SP600125 distributor | buy 129-56-6| 129-56-6 Supplier | purchase 129-56-6 | 129-56-6 cost | 129-56-6 manufacturer | order 129-56-6 | 129-56-6 distributor