SP600125

Name: SP600125
SKU: A10860
Price: 40 USD
Rating: 5 (8 reviews)

Catalog No.: A10860

JNK inhibitor

Adooq's SP600125 has been cited by 8 publications

SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3.

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Grouped product items
Size	Price	Stock
10mg	$40.00	In stock
50mg	$55.00	In stock
200mg	$100.00	In stock
*10mM 1mL in DMSO**	$50.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's SP600125 has been cited by 8 publications

Peiling Zhang, .et al. , Regen Biomater, 2023, Sep 7:10:rbad079 PMID: 38020237

Tetsuya Kouno, .et al. , J Biol Chem, 2022, Jul;298(7):102056 PMID: 35605662

Mark P Roberto, .et al. , Immunity, 2021, Aug 10;54(8):1807-1824.e14 PMID: 34380064

Yang PM, .et al. , Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078

Byungki Jang, .et al. , Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055

Yuki Haga, .et al. , PLoS One, 2017, 12(3): e0174153 PMID: 28323861

Jia-Shiuan Tsai, .et al. , PLoS One, 2016, 11(1): e0147011 PMID: 26751215

Choe YJ, .et al. , Int J Oncol., 2014, 44(3):761-8. PMID: 24366007

Biological Activity

Discription

SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3.

Targets

Target	Value

Product Information

Catalog Num	A10860
Formula	C14H8N2O
Molecular Weight	220.2
CAS Number	129-56-6
SMILES	C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	43 mg/mL (195.25 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	45.41 mL	227.07 mL	454.13 mL
0.5 mM	9.08 mL	45.41 mL	90.83 mL
1 mM	4.54 mL	22.71 mL	45.41 mL
5 mM	0.91 mL	4.54 mL	9.08 mL

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