SP600125

Catalog No.: A10860
JNK inhibitor
SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3.
Grouped product items
Product Name Price Stock Qty
SP600125 10mg
$40.00
In stock
SP600125 50mg
$55.00
In stock
SP600125 200mg
$100.00
In stock
SP600125 10mM * 1mL in DMSO
$50.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's SP600125 has been cited by 8 publications
  • Peiling Zhang, .et al. , Regen Biomater, 2023, Sep 7:10:rbad079 PMID: 38020237
  • Tetsuya Kouno, .et al. , J Biol Chem, 2022, Jul;298(7):102056 PMID: 35605662
  • Mark P Roberto, .et al. , Immunity, 2021, Aug 10;54(8):1807-1824.e14 PMID: 34380064
  • Yang PM, .et al. , Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
  • Byungki Jang, .et al. , Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055
  • Yuki Haga, .et al. , PLoS One, 2017, 12(3): e0174153 PMID: 28323861
  • Jia-Shiuan Tsai, .et al. , PLoS One, 2016, 11(1): e0147011 PMID: 26751215
  • Choe YJ, .et al. , Int J Oncol., 2014, 44(3):761-8. PMID: 24366007
  • Biological Activity
    Discription SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3.
    Targets
    Target Value
    Product Information
    Catalog Num A10860
    Formula C14H8N2O
    Molecular Weight 220.2
    CAS Number 129-56-6
    SMILES C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 43 mg/mL (195.25 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 45.41 mL 227.07 mL 454.13 mL
    0.5 mM 9.08 mL 45.41 mL 90.83 mL
    1 mM 4.54 mL 22.71 mL 45.41 mL
    5 mM 0.91 mL 4.54 mL 9.08 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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