SPA107 is a tubulin inhibitor that prevents tubulin polymerization, demonstrating potent antimitotic activity with an IC50 of 0.5 nM. In addition, SPA107 exhibits significant cytotoxic effects in p53 mutated MCF-7 cells, with an IC50 of 0.5 nM. This compound is valuable for research in cancer biology, particularly in studies focused on mitotic disruption and the mechanisms underlying drug resistance.
SPA107 is a tubulin inhibitor that prevents tubulin polymerization, demonstrating potent antimitotic activity with an IC50 of 0.5 nM. In addition, SPA107 exhibits significant cytotoxic effects in p53 mutated MCF-7 cells, with an IC50 of 0.5 nM. This compound is valuable for research in cancer biology, particularly in studies focused on mitotic disruption and the mechanisms underlying drug resistance.
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