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SR 3677 dihydrochloride

ROCK inhibitor

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Catalog No. A12674

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SR 3677 dihydrochloride 10mg A12674-10
SR 3677 dihydrochloride 25mg A12674-25
SR 3677 dihydrochloride 50mg A12674-50
SR 3677 dihydrochloride 100mg A12674-100

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).

SR 3677 dihydrochloride

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Chemical Information

Catalog Num A12674
Actions Inhibitor
M. Wt 481.37
Formula C22H24N4O4.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1072959-67-1
Synonyms SR3677, SR-3677

Biological Activity

SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.77 mL 103.87 mL 207.74mL
0.5 mM 4.15 mL 20.77 mL 41.55 mL
1 mM 2.08 mL 10.39 mL 20.77 mL
5 mM 0.42 mL 2.08 mL 4.15 mL

*The above data is based on the productmolecular weight 481.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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