SR 3677 dihydrochloride

Catalog No.: A12674

ROCK inhibitor

SR 3677 dihydrochloride

SR 3677 dihydrochloride Chemical Structure

CAS NO. 1072959-67-1

SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$320.00
100 mg
$550.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.77 mL 103.87 mL 207.74 mL
0.5 mM 4.15 mL 20.77 mL 41.55 mL
1 mM 2.08 mL 10.39 mL 20.77 mL
5 mM 0.42 mL 2.08 mL 4.15 mL

*The above data is based on the productmolecular weight 481.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12674
Actions Inhibitor
M. Wt 481.37
Formula C22H24N4O4.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1072959-67-1
Synonyms SR3677, SR-3677
SMILES CN(C)CCOC1=C(C=CC(=C1)C2=CNN=C2)NC(=O)C3COC4=CC=CC=C4O3

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