SR33805 oxalate is a potent calcium (Ca2+) channel antagonist, specifically blocking L-type calcium channels. It demonstrates effective inhibition with EC50 values of 4.1 nM in depolarized conditions and 33 nM under polarized conditions. This reagent is valuable for research into acute and chronic heart failure, aiding in the understanding of Ca2+ signaling in cardiac pathophysiology.
SR33805 oxalate is a potent calcium (Ca2+) channel antagonist, specifically blocking L-type calcium channels. It demonstrates effective inhibition with EC50 values of 4.1 nM in depolarized conditions and 33 nM under polarized conditions. This reagent is valuable for research into acute and chronic heart failure, aiding in the understanding of Ca2+ signaling in cardiac pathophysiology.
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