SRPIN340

Catalog No.: A13188
SRPK inhibitor
SRPIN340 is a cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50 = 0.14 and 1.8 μM, respectively, against mSRPK1 and mSRPK2) with much reduced activity against 143 other kinases.
Grouped product items
Product Name Price Stock Qty
SRPIN340 5mg
$60.00
In stock
SRPIN340 10mg
$100.00
In stock
SRPIN340 25mg
$200.00
In stock
SRPIN340 50mg
$350.00
In stock
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Biological Activity
Discription SRPIN340 is a cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50 = 0.14 and 1.8 μM, respectively, against mSRPK1 and mSRPK2) with much reduced activity against 143 other kinases.
Targets
Target Value
Product Information
Catalog Num A13188
Formula C18H18F3N3O
Molecular Weight 349.4
CAS Number 218156-96-8
SMILES C1CCN(CC1)C2=C(C=C(C=C2)C(F)(F)F)NC(=O)C3=CC=NC=C3
Synonyms SRPIN 340, SRPIN-340
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 67 mg/mL (191.78 mM)
Water Insoluble
Ethanol 67 mg/mL (191.78 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.62 mL 143.1 mL 286.2 mL
0.5 mM 5.72 mL 28.62 mL 57.24 mL
1 mM 2.86 mL 14.31 mL 28.62 mL
5 mM 0.57 mL 2.86 mL 5.72 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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