STING agonist-12

Catalog No.: A65546
STING Activator
STING agonist-12 (Compound 53) is a potent agonist that activates the human stimulator of interferon genes (STING) pathway, exhibiting an EC50 value of 185 nM. This compound serves as a valuable tool for immunological research, particularly in studying innate immune responses and antitumor immunity. Its ability to modulate STING activity makes it a promising candidate for assessing therapeutic strategies in cancer and infectious diseases.
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
5mg
$65.00
In stock
10mg
$105.00
In stock
25mg
$220.00
In stock
50mg
$345.00
In stock
100mg
$500.00
In stock
200mg
$695.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSTING agonist-12 (Compound 53) is a potent agonist that activates the human stimulator of interferon genes (STING) pathway, exhibiting an EC50 value of 185 nM. This compound serves as a valuable tool for immunological research, particularly in studying innate immune responses and antitumor immunity. Its ability to modulate STING activity makes it a promising candidate for assessing therapeutic strategies in cancer and infectious diseases.
Product Information
Catalog NumA65546
FormulaC25H19ClF4N2O2
Molecular Weight490.88
CAS Number2259624-71-8
SMILESClC1=CC=CC(F)=C1CN2C3=C(C(C)(C2=O)C)C=CC(C(NCC4=C(C=C(C=C4F)F)F)=O)=C3
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