STING agonist-24

Catalog No.: A65603
STING Agonist
STING Agonist-24 is a small-molecule STING agonist that activates the STING pathway, leading to increased phosphorylation of STING, TBK1, and IRF3. This compound enhances the expression of key pro-inflammatory cytokines and chemokines, including IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5, in tumor cells. Additionally, STING Agonist-24 demonstrates antiviral activity against various strains of SARS-CoV, making it a valuable tool for research in immunotherapy and viral pathogenesis.
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Size Stock
5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSTING Agonist-24 is a small-molecule STING agonist that activates the STING pathway, leading to increased phosphorylation of STING, TBK1, and IRF3. This compound enhances the expression of key pro-inflammatory cytokines and chemokines, including IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5, in tumor cells. Additionally, STING Agonist-24 demonstrates antiviral activity against various strains of SARS-CoV, making it a valuable tool for research in immunotherapy and viral pathogenesis.
Product Information
Catalog NumA65603
FormulaC34H37N13O5
Molecular Weight707.74
CAS Number2408722-91-6
SMILESO=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OC)C=C(C(N)=O)C=C5N=C4NC(C6=CC(C)=NN6CC)=O
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