STING agonist-26 (CF508) is a small-molecule agonist that activates the Stimulator of Interferon Genes (STING) pathway. This compound enhances the phosphorylation of STING, TBK1, and IRF3, leading to increased production of key cytokines, including IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5, in tumor cells. STING agonist-26 shows potential in the study of antiviral responses, particularly against SARS-CoV strains, making it a valuable tool for research in immunotherapy and inflammation.
STING agonist-26 (CF508) is a small-molecule agonist that activates the Stimulator of Interferon Genes (STING) pathway. This compound enhances the phosphorylation of STING, TBK1, and IRF3, leading to increased production of key cytokines, including IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5, in tumor cells. STING agonist-26 shows potential in the study of antiviral responses, particularly against SARS-CoV strains, making it a valuable tool for research in immunotherapy and inflammation.
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