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Sulfone-Bis-PEG4-acid

Catalog No.: A83086
PROTAC Linkers
Sulfone-Bis-PEG4-acid is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound facilitates the assembly of bifunctional molecules that promote targeted protein degradation, making it valuable in biological research and drug discovery applications. Its unique structural properties enhance solubility and optimize the pharmacokinetic profiles of PROTACs.
Sulfone-Bis-PEG4-acid 2055024-37-6 PROTAC Linkers
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSulfone-Bis-PEG4-acid is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound facilitates the assembly of bifunctional molecules that promote targeted protein degradation, making it valuable in biological research and drug discovery applications. Its unique structural properties enhance solubility and optimize the pharmacokinetic profiles of PROTACs.
Product Information
Catalog NumA83086
FormulaC22H42O14S
Molecular Weight562.63
CAS Number2055024-37-6
SMILESO=C(O)CCOCCOCCOCCOCCS(CCOCCOCCOCCOCCC(O)=O)(=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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