T-226296 is a selective antagonist of the melanin-concentrating hormone receptor, exhibiting IC50 values of 5.5 nM and 8.6 nM for human and rat SLC-1, respectively. This compound demonstrates potential in modulating weight and metabolic processes, making it useful in research on obesity and insulin resistance. Its oral bioavailability facilitates in vivo studies, providing insights into the role of melanin-concentrating hormone signaling in metabolic disorders.
T-226296 is a selective antagonist of the melanin-concentrating hormone receptor, exhibiting IC50 values of 5.5 nM and 8.6 nM for human and rat SLC-1, respectively. This compound demonstrates potential in modulating weight and metabolic processes, making it useful in research on obesity and insulin resistance. Its oral bioavailability facilitates in vivo studies, providing insights into the role of melanin-concentrating hormone signaling in metabolic disorders.
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