t-Boc-Aminooxy-PEG2-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group, facilitating its engagement in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities containing DBCO or BCN groups, making it an essential tool for biochemical research and development in targeted protein degradation studies.
t-Boc-Aminooxy-PEG2-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group, facilitating its engagement in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities containing DBCO or BCN groups, making it an essential tool for biochemical research and development in targeted protein degradation studies.
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