t-Boc-Aminooxy-PEG3-alcohol

Catalog No.: A83421
PROTAC Linkers
t-Boc-Aminooxy-PEG3-alcohol is a PEG-based linker designed for use in the synthesis of PROTAC (PROteolysis TArgeting Chimeras) compounds. Its aminooxy group facilitates selective conjugation to target proteins, enabling the development of bifunctional molecules that direct E3 ligase-mediated protein degradation. This linker is valuable for researchers seeking to explore targeted protein modulation and therapeutic applications in the field of targeted protein degradation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiont-Boc-Aminooxy-PEG3-alcohol is a PEG-based linker designed for use in the synthesis of PROTAC (PROteolysis TArgeting Chimeras) compounds. Its aminooxy group facilitates selective conjugation to target proteins, enabling the development of bifunctional molecules that direct E3 ligase-mediated protein degradation. This linker is valuable for researchers seeking to explore targeted protein modulation and therapeutic applications in the field of targeted protein degradation.
Product Information
Catalog NumA83421
FormulaC11H23NO6
Molecular Weight265.30
CAS Number252378-66-8
SMILESO=C(OC(C)(C)C)NOCCOCCOCCO
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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