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Taccalonolide AJ

Catalog No.: A54839
Microtubule Inhibitor
Taccalonolide AJ is a microtubule stabilizing compound with significant antiproliferative properties. This semi-synthetic reagent demonstrates high potency against cancer cells, exhibiting an IC50 of 4.2 nM in HeLa cell lines. Its mechanism of action involves the stabilization of microtubules, making it a valuable tool for research in cancer biology and therapeutic development.
Taccalonolide AJ 2230777-09-8 Microtubule Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$185.00
In stock
5mg
$565.00
In stock
10mg
$1,010.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTaccalonolide AJ is a microtubule stabilizing compound with significant antiproliferative properties. This semi-synthetic reagent demonstrates high potency against cancer cells, exhibiting an IC50 of 4.2 nM in HeLa cell lines. Its mechanism of action involves the stabilization of microtubules, making it a valuable tool for research in cancer biology and therapeutic development.
Product Information
Catalog NumA54839
FormulaC34H44O14
Molecular Weight676.70
CAS Number2230777-09-8
SMILESC[C@]1([C@@]2(O)C)[C@]3(OC2=O)[C@H]([C@@H](C)[C@@]4([H])[C@@]1([H])[C@@H]([C@]5([H])[C@@]4([C@H]([C@@H](OC(C)=O)[C@@]6([H])[C@@]5([H])[C@H](C([C@]7([H])[C@@]6([C@H]([C@@H](O8)[C@@H]8C7)OC(C)=O)C)=O)O)OC(C)=O)C)O)O3
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Cytoskeleton > Microtubule/Tubulin