Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively).
Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively).
Product Information
Catalog Num
A17374
Formula
C13H15ClN2
Molecular Weight
234.73
CAS Number
1684-40-8
SMILES
NC1=C(CCCC2)C2=NC3=CC=CC=C31.[H]Cl
Synonyms
Hydroaminacrine; NSC72108; NSC-72108; NSC72108
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
44 mg/mL (187.45 mM)
Water
44 mg/mL (187.45 mM)
Ethanol
44 mg/mL (187.45 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: