Tacrine HCl

Catalog No.: A17374

AChE & butyrylcholinesterase inhibitor

Tacrine HCl

Tacrine HCl Chemical Structure

CAS NO. 1684-40-8

Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively).

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5000 mg
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Biological Activity

Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively).
In vitro DMSO 44 mg/mL (187.45 mM)
Water 44 mg/mL (187.45 mM)
Ethanol 44 mg/mL (187.45 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 42.6 mL 213.01 mL 426.02 mL
0.5 mM 8.52 mL 42.6 mL 85.2 mL
1 mM 4.26 mL 21.3 mL 42.6 mL
5 mM 0.85 mL 4.26 mL 8.52 mL

*The above data is based on the productmolecular weight 234.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17374
Actions Inhibitor
CAS No. 1684-40-8
Formula C13H15ClN2
M. Wt 234.73
Solubility DMSO
Purity >98%
Synonyms Hydroaminacrine; NSC72108; NSC-72108; NSC72108
SMILES NC1=C(CCCC2)C2=NC3=CC=CC=C31.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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