TAK-875 (Fasiglifam)
TAK-875 is a potent, selective, and orally bioavailable GPR40 agonist.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's TAK-875 (Fasiglifam) has been cited by 3 publications
- Ying Liu, .et al. , Nucleic Acids Res, 2018, Oct 12; 46(18): 9864-9874 PMID: 30219861
- Deborah A. Goldspink, .et al. , Mol Metab, 2018, Jan; 7: 90-101 PMID: 29167062
- Hodaka Yamada, .et al. , Sci Rep, 2016, 6: 25912 PMID: 27180622
Biological Activity
| Description | TAK-875 is a potent, selective, and orally bioavailable GPR40 agonist. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
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Product Information
| Catalog Num | A11018 |
|---|---|
| Formula | C29H32O7S |
| Molecular Weight | 524.6 |
| CAS Number | 1000413-72-8 |
| SMILES | CC1=C(C2=CC(COC3=CC=C([C@H](CC(O)=O)CO4)C4=C3)=CC=C2)C(C)=CC(OCCCS(C)(=O)=O)=C1 |
| Synonyms | TAK875 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 92 mg/mL (172.4 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 0.5% CMC+0.25% Tween 80 | 28 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.06 mL | 95.31 mL | 190.62 mL |
| 0.5 mM | 3.81 mL | 19.06 mL | 38.12 mL |
| 1 mM | 1.91 mL | 9.53 mL | 19.06 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.81 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
