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Talnetant is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.15 mL | 130.74 mL | 261.47 mL |
| 0.5 mM | 5.23 mL | 26.15 mL | 52.29 mL |
| 1 mM | 2.61 mL | 13.07 mL | 26.15 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.23 mL |
*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15254 |
|---|---|
| Actions | Antagonist |
| CAS No. | 174636-32-9 |
| Formula | C25H22N2O2 |
| M. Wt | 382.45 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | SB-223412, SB223412, SB 223412 |
| SMILES | CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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