Talnetant

Catalog No.: A15254

NK3 receptor antagonist

Talnetant Chemical Structure

CAS NO. 174636-32-9

Talnetant is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.

Availability: In stock

Package Price Qty
10 mg
$128.00
25 mg
$280.00
50 mg
$500.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Talnetant is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.15 mL 130.74 mL 261.47 mL
0.5 mM 5.23 mL 26.15 mL 52.29 mL
1 mM 2.61 mL 13.07 mL 26.15 mL
5 mM 0.52 mL 2.61 mL 5.23 mL

*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15254
Actions Antagonist
M. Wt 382.45
Formula C25H22N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 174636-32-9
Synonyms SB-223412, SB223412, SB 223412
SMILES CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O

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