Taltobulin trifluoroacetate

Catalog No.: A31472
Tubulin Inhibitor
Taltobulin trifluoroacetate is a potent tubulin inhibitor that targets microtubule dynamics. This synthetic analogue of hemiasterlin effectively inhibits the polymerization of purified tubulin, leading to disrupted microtubule organization within cells. Taltobulin trifluoroacetate induces mitotic arrest and apoptosis, making it a valuable compound for research in cancer biology and studies focused on overcoming P-glycoprotein-mediated drug resistance.
Grouped product items
Size Price Stock Qty
5mg
$180.00
In stock
10mg
$285.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTaltobulin trifluoroacetate is a potent tubulin inhibitor that targets microtubule dynamics. This synthetic analogue of hemiasterlin effectively inhibits the polymerization of purified tubulin, leading to disrupted microtubule organization within cells. Taltobulin trifluoroacetate induces mitotic arrest and apoptosis, making it a valuable compound for research in cancer biology and studies focused on overcoming P-glycoprotein-mediated drug resistance.
Product Information
Catalog NumA31472
FormulaC29H44F3N3O6
Molecular Weight587.67
CAS Number228266-41-9
SMILESCC(C)(C)[C@H](NC([C@H](C(C)(C1=CC=CC=C1)C)NC)=O)C(N([C@@H](C(C)C)/C=C(C(O)=O)\C)C)=O.O=C(O)C(F)(F)F
SynonymsHTI-286 trifluoroacetate; SPA-110 trifluoroacetate
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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