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Catalog No.: A21264

tubulin inhibitor


Taltobulin Chemical Structure

CAS NO. 228266-40-8

altobulin (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.

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Biological Activity

altobulin (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.11 mL 105.56 mL 211.13 mL
0.5 mM 4.22 mL 21.11 mL 42.23 mL
1 mM 2.11 mL 10.56 mL 21.11 mL
5 mM 0.42 mL 2.11 mL 4.22 mL

*The above data is based on the productmolecular weight 473.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21264
Actions Inhibitor
CAS No. 228266-40-8
Formula C27H43N3O4
M. Wt 473.65
Purity >98%
Synonyms HTI-286; SPA-110
SMILES CC(C)(C)[[email protected]](NC([[email protected]](C(C)(C1=CC=CC=C1)C)NC)=O)C(N([[email protected]@H](C(C)C)/C=C(C(O)=O)\C)C)=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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