Tampramine is a phenothiazine derivative that functions as a multidrug resistance (MDR) reversal agent. It demonstrates significant biological activity with effective doses (ED50) of 60 μM in both P388 and P388/ADR cell lines. Tampramine is primarily used in research to explore mechanisms of drug resistance and to enhance the efficacy of chemotherapeutic agents.
Tampramine is a phenothiazine derivative that functions as a multidrug resistance (MDR) reversal agent. It demonstrates significant biological activity with effective doses (ED50) of 60 μM in both P388 and P388/ADR cell lines. Tampramine is primarily used in research to explore mechanisms of drug resistance and to enhance the efficacy of chemotherapeutic agents.
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