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$0.00 Biological Activity
TAS-102 is an orally bioavailable combination agent composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2??-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI), with potential antineoplastic activity,
| In vitro | DMSO | Warmed: 88 mg/mL (100.97 mM) | |
| Water | Warmed: 13 mg/mL (14.92 mM) | ||
| Ethanol | 88 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.38 mL | 86.91 mL | 173.82 mL |
| 0.5 mM | 3.48 mL | 17.38 mL | 34.76 mL |
| 1 mM | 1.74 mL | 8.69 mL | 17.38 mL |
| 5 mM | 0.35 mL | 1.74 mL | 3.48 mL |
*The above data is based on the productmolecular weight 575.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15533 |
|---|---|
| CAS No. | 733030-01-8 |
| Formula | C19H23Cl2F3N6O7 |
| M. Wt | 575.3 |
| Purity | >98% |
| Synonyms | TAS102, TAS 102, Lonsurf |
| SMILES | C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl.C1[[email protected]@H]([[email protected]](O[[email protected]]1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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