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Chemical Information
| Catalog Num | A15533 |
|---|---|
| Actions | No |
| M. Wt | 871.53 |
| Formula | C29H34Cl2F6N8O12 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 733030-01-8 |
| Synonyms | TAS102, TAS 102 |
| SMILES code | O=C1NC(C(C(F)(F)F)=CN1[[email protected]@H]2O[[email protected]](CO)[[email protected]@H](O)C2)=O.O=C3NC(C(Cl)=C(CN4C(CCC4)=N)N3)=O.[H]Cl |
| Chemical Name | N/A |
Description |
TAS-102 is an orally bioavailable combination agent composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2??-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI), with potential antineoplastic activity, | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.47 mL | 57.37 mL | 114.74mL |
| 0.5 mM | 2.29 mL | 11.47 mL | 22.95 mL |
| 1 mM | 1.15 mL | 5.74 mL | 11.47 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.29 mL |
*The above data is based on the productmolecular weight 871.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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