TAS-102

Catalog No.: A15533
Trifluridine-tipiracil hydrochloride mixture
TAS-102 is an orally bioavailable combination agent composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2??-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI), with potential antineoplastic activity,
Grouped product items
Product Name Price Stock Qty
TAS-102 2mg
Special Price $32.00 Regular Price $40.00
In stock
TAS-102 5mg
Special Price $44.00 Regular Price $55.00
In stock
TAS-102 10mg
Special Price $72.00 Regular Price $90.00
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Biological Activity
Discription TAS-102 is an orally bioavailable combination agent composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2??-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI), with potential antineoplastic activity,
Product Information
Catalog Num A15533
Formula C19H23Cl2F3N6O7
Molecular Weight 575.3
CAS Number 733030-01-8
SMILES C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl.C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O.Cl
Synonyms TAS102, TAS 102, Lonsurf
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 88 mg/mL (100.97 mM)
Water Warmed: 13 mg/mL (14.92 mM)
Ethanol 88 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.38 mL 86.91 mL 173.82 mL
0.5 mM 3.48 mL 17.38 mL 34.76 mL
1 mM 1.74 mL 8.69 mL 17.38 mL
5 mM 0.35 mL 1.74 mL 3.48 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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