TAS4464 hydrochloride

Catalog No.: A21708

NEDD8 activating enzyme inhibitor

TAS4464 hydrochloride

TAS4464 hydrochloride Chemical Structure

CAS NO. 1848959-11-4

TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.

Availability: In stock

Package Price Qty
5 mg
$315.00
10 mg
$543.00
50 mg
$1,610.00
100 mg
$3,220.00
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Biological Activity

TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.42 mL 92.09 mL 184.17 mL
0.5 mM 3.68 mL 18.42 mL 36.83 mL
1 mM 1.84 mL 9.21 mL 18.42 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 542.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21708
Actions Inhibitor
M. Wt 542.97
Formula C21H24ClFN6O6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1848959-11-4
Synonyms TAS 4464, TAS-4464
SMILES NC1=NC=NC2=C1C(C#CC3=C(F)C=CC=C3OCC)=CN2[[email protected]@H]4O[[email protected]](CNS(=O)(N)=O)[[email protected]@H](O)[[email protected]]4O.Cl

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