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Taxinine B

Catalog No.: A54909
Microtubule Inhibitor
Taxinine B is a microtubule inhibitor derived from the Japanese Yew (Taxus cuspidata). It effectively inhibits CaCl2-induced depolymerization of microtubules, contributing to its potential in cancer research. Taxinine B may also be valuable for overcoming multidrug resistance in tumor cells, making it a significant compound for studies focused on cancer treatment and cellular mechanisms.
Taxinine B 18457-44-8 Microtubule Inhibitor
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Size Price Stock Qty
5mg
$580.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTaxinine B is a microtubule inhibitor derived from the Japanese Yew (Taxus cuspidata). It effectively inhibits CaCl2-induced depolymerization of microtubules, contributing to its potential in cancer research. Taxinine B may also be valuable for overcoming multidrug resistance in tumor cells, making it a significant compound for studies focused on cancer treatment and cellular mechanisms.
Product Information
Catalog NumA54909
FormulaC37H44O11
Molecular Weight664.74
CAS Number18457-44-8
SMILESO=C(O[C@H](C1=C)C[C@H](OC(C)=O)[C@]([C@@H](OC(C)=O)[C@H](OC(C)=O)C2=C3C)(C)[C@]1([H])[C@H](OC(C)=O)[C@](C2(C)C)([H])CC3=O)/C=C/C4=CC=CC=C4
SynonymsTaxinin B
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Cytoskeleton > Microtubule/Tubulin