Tazemetostat hydrobromide

Catalog No.: A21759

EZH2 inhibitor

Tazemetostat hydrobromide

Tazemetostat hydrobromide Chemical Structure

CAS NO. 1467052-75-0

Tazemetostat hydrobromide (EPZ-6438 hydrobromide) is a potent, selective and orally available EZH2 inhibitor.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $54.00

Special Price $43.20

10 mg

Regular Price: $93.00

Special Price $74.40

50 mg

Regular Price: $276.00

Special Price $220.80

100 mg

Regular Price: $552.00

Special Price $441.60

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Biological Activity

Tazemetostat hydrobromide (EPZ-6438 hydrobromide) is a potent, selective and orally available EZH2 inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.3 mL 76.49 mL 152.99 mL
0.5 mM 3.06 mL 15.3 mL 30.6 mL
1 mM 1.53 mL 7.65 mL 15.3 mL
5 mM 0.31 mL 1.53 mL 3.06 mL

*The above data is based on the productmolecular weight 653.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21759
Actions Inhibitor
CAS No. 1467052-75-0
Formula C34H45BrN4O4
M. Wt 653.65
Purity >98%
Synonyms EPZ-6438 hydrobromide, EPZ6438, EPZ 6438; E-7438 hydrobromide, E 7438, E7438
SMILES O=C(C1=CC(C2=CC=C(CN3CCOCC3)C=C2)=CC(N(CC)C4CCOCC4)=C1C)NCC5=C(C)C=C(C)NC5=O.[H]Br
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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