TC-A-2317 HCl

Catalog No.: A13567

Aurora kinase A inhibitor

TC-A-2317 HCl Chemical Structure

CAS NO. 1245907-03-2

TC-A-2317 hydrochloride is a potent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor activity.

Availability: In stock

Package Price Qty
10 mg
$180.00
25 mg
$360.00
50 mg
$650.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TC-A-2317 hydrochloride is a potent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.45 mL 127.25 mL 254.5 mL
0.5 mM 5.09 mL 25.45 mL 50.9 mL
1 mM 2.54 mL 12.72 mL 25.45 mL
5 mM 0.51 mL 2.54 mL 5.09 mL

*The above data is based on the productmolecular weight 392.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13567
Actions Inhibitor
M. Wt 392.93
Formula C19H28N6O.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1245907-03-2
Synonyms TCA2317
SMILES CC(CCCC(C)(C)O)NC1=NC(NC2=NNC(C)=C2)=CC(C)=C1[N+]#[C-].Cl

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