TCS 21311

Catalog No.: A15365
JAK3 inhibitor
TCS 21311 is a potent JAK3 inhibitor (IC50 = 8 nM). TCS 21311 is selective for JAK3 over JAK1, JAK2 and Tyk 2 (IC50 values are 1017, 2550 and 8055 nM respectively).
Grouped product items
Size Price Stock Qty
1mg
$50.00
In stock
5mg
$180.00
In stock
10mg
$320.00
In stock
25mg
$625.00
In stock
50mg
$785.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription TCS 21311 is a potent JAK3 inhibitor (IC50 = 8 nM). TCS 21311 is selective for JAK3 over JAK1, JAK2 and Tyk 2 (IC50 values are 1017, 2550 and 8055 nM respectively).
Targets
Target Value
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A15365
Formula C27H25F3N4O4
Molecular Weight 526.51
CAS Number 1260181-14-3
SMILES CC(C)(C(=O)N1CCN(CC1)C2=CC(=C(C=C2)C(F)(F)F)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54)O
Synonyms TCS21311, TCS-21311
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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